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Receptor Interactive Protein Kinase 3 Promotes Cisplatin-Triggered Necrosis in Apoptosis-Resistant Esophageal Squamous Cell Carcinoma Cells

Cisplatin-based chemotherapy is currently the standard treatment for locally advanced esophageal cancer. Cisplatin has been shown to induce both apoptosis and necrosis in cancer cells, but the mechanism by which programmed necrosis is induced remains unknown. In this study, we provide evidence that...

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Detalles Bibliográficos
Autores principales: Xu, Yang, Lin, Zhengwei, Zhao, Nan, Zhou, Lanping, Liu, Fang, Cichacz, Zbigniew, Zhang, Lin, Zhan, Qimin, Zhao, Xiaohang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069059/
https://www.ncbi.nlm.nih.gov/pubmed/24959694
http://dx.doi.org/10.1371/journal.pone.0100127