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Chimeric Avidin – NMR Structure and Dynamics of a 56 kDa Homotetrameric Thermostable Protein
Chimeric avidin (ChiAVD) is a product of rational protein engineering remarkably resistant to heat and harsh conditions. In quest of the fundamentals behind factors affecting stability we have elucidated the solution NMR spectroscopic structure of the biotin–bound form of ChiAVD and characterized th...
Autores principales: | Tossavainen, Helena, Kukkurainen, Sampo, Määttä, Juha A. E., Kähkönen, Niklas, Pihlajamaa, Tero, Hytönen, Vesa P., Kulomaa, Markku S., Permi, Perttu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069078/ https://www.ncbi.nlm.nih.gov/pubmed/24959850 http://dx.doi.org/10.1371/journal.pone.0100564 |
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