Non-Heme-Binding Domains and Segments of the Staphylococcus aureus IsdB Protein Critically Contribute to the Kinetics and Equilibrium of Heme Acquisition from Methemoglobin

The hemoglobin receptor IsdB rapidly acquires heme from methemoglobin (metHb) in the heme acquisition pathway of Staphylococcus aureus. IsdB consists of N-terminal segment (NS), NEAT1 (N1), middle (MD), and heme binding NEAT2 (N2) domains, and C-terminal segment (CS). This study aims to elucidate th...

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Detalles Bibliográficos
Autores principales: Zhu, Hui, Li, Dengfeng, Liu, Mengyao, Copié, Valerie, Lei, Benfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069089/
https://www.ncbi.nlm.nih.gov/pubmed/24959723
http://dx.doi.org/10.1371/journal.pone.0100744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069089/
https://www.ncbi.nlm.nih.gov/pubmed/24959723
http://dx.doi.org/10.1371/journal.pone.0100744

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