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Progression-free survival as a potential surrogate for overall survival in metastatic breast cancer

BACKGROUND: Progression-free survival (PFS) and time to progression (TTP) are frequently used to establish the clinical efficacy of anti-cancer drugs. However, the surrogacy of PFS/TTP for overall survival (OS) remains a matter of uncertainty in metastatic breast cancer (mBC). This study assessed th...

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Detalles Bibliográficos
Autores principales: Beauchemin, Catherine, Cooper, Dan, Lapierre, Marie-Ève, Yelle, Louise, Lachaine, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069144/
https://www.ncbi.nlm.nih.gov/pubmed/24971020
http://dx.doi.org/10.2147/OTT.S63302