Nuclear MEK1 Sequesters PPARγ and Bisects MEK1/ERK Signaling: A Non-Canonical Pathway of Retinoic Acid Inhibition of Adipocyte Differentiation

Uncontrolled adipogenesis and adipocyte proliferation have been connected to human comorbidities. Retinoic acid (RA) is known to inhibit adipocyte differentiation, however the underlying mechanisms have not been adequately understood. This study reports that RA acting as a ligand to RA receptors (RA...

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Detalles Bibliográficos
Autores principales: Dave, Sandeep, Nanduri, Ravikanth, Dkhar, Hedwin Kitdorlang, Bhagyaraj, Ella, Rao, Alka, Gupta, Pawan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069188/
https://www.ncbi.nlm.nih.gov/pubmed/24959884
http://dx.doi.org/10.1371/journal.pone.0100862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069188/
https://www.ncbi.nlm.nih.gov/pubmed/24959884
http://dx.doi.org/10.1371/journal.pone.0100862

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