Rad23 escapes degradation because it lacks a proteasome initiation region

Rad23 is an adaptor protein that binds to both ubiquitinated substrates and to the proteasome. Despite its association with the proteasome, Rad23 escapes degradation. Here we show that Rad23 remains stable because it lacks an effective initiation region where the proteasome can engage the protein an...

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Detalles Bibliográficos
Autores principales: Fishbain, Susan, Prakash, Sumit, Herrig, Annie, Elsasser, Suzanne, Matouschek, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069258/
https://www.ncbi.nlm.nih.gov/pubmed/21304521
http://dx.doi.org/10.1038/ncomms1194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069258/
https://www.ncbi.nlm.nih.gov/pubmed/21304521
http://dx.doi.org/10.1038/ncomms1194

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