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Long term exposure to L-arginine accelerates endothelial cell senescence through arginase-II and S6K1 signaling

L-arginine supplementation is proposed to improve health status or as adjunct therapy for diseases including cardiovascular diseases. However, controversial results and even detrimental effects of L-arginine supplementation are reported. We investigate potential mechanisms of L-arginine-induced detr...

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Detalles Bibliográficos
Autores principales: Xiong, Yuyani, Fru, Michael Forbiteh, Yu, Yi, Montani, Jean-Pierre, Ming, Xiu-Fen, Yang, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069264/
https://www.ncbi.nlm.nih.gov/pubmed/24860943