Role of Gag and lipids during HIV-1 assembly in CD4(+) T cells and macrophages

HIV-1 is an RNA enveloped virus that preferentially infects CD4(+) T lymphocytes and also macrophages. In CD4(+) T cells, HIV-1 mainly buds from the host cell plasma membrane. The viral Gag polyprotein targets the plasma membrane and is the orchestrator of the HIV assembly as its expression is suffi...

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Detalles Bibliográficos
Autores principales: Mariani, Charlotte, Desdouits, Marion, Favard, Cyril, Benaroch, Philippe, Muriaux, Delphine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069574/
https://www.ncbi.nlm.nih.gov/pubmed/25009540
http://dx.doi.org/10.3389/fmicb.2014.00312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069574/
https://www.ncbi.nlm.nih.gov/pubmed/25009540
http://dx.doi.org/10.3389/fmicb.2014.00312

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