Calcitriol May Down-Regulate mRNA Over-Expression of Toll-Like Receptor-2 and -4, LL-37 and Proinflammatory Cytokines in Cultured Human Keratinocytes

BACKGROUND: Although vitamin D analogs have been used in the topical treatment of psoriasis, their mechanisms of action are not well understand. Calcitriol, the hormonally active vitamin D3 metabolite, has been demonstrated to exert immunomodulatory effects in the skin by down-regulating the express...

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Detalles Bibliográficos
Autores principales: Jeong, Mi Sook, Kim, Ji-Yun, Lee, He In, Seo, Seong Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Dermatological Association; The Korean Society for Investigative Dermatology 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069638/
https://www.ncbi.nlm.nih.gov/pubmed/24966627
http://dx.doi.org/10.5021/ad.2014.26.3.296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069638/
https://www.ncbi.nlm.nih.gov/pubmed/24966627
http://dx.doi.org/10.5021/ad.2014.26.3.296

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