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Suppression of metastasis by mirtazapine via restoration of the Lin-7C/β-catenin pathway in human cancer cells

No definitive therapy exists to treat human metastatic tumors. We reported previously that down-regulation of Lin-7C is essential for metastasis of human squamous cell carcinomas (hSCCs). In this study, we investigated the chemical restoration of Lin-7C expression and demonstrated its effectiveness...

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Detalles Bibliográficos
Autores principales: Uzawa, Katsuhiro, Kasamatsu, Atsushi, Shimizu, Toshihiro, Saito, Yasuhiro, Baba, Takao, Sakuma, Kentaro, Fushimi, Kazuaki, Sakamoto, Yosuke, Ogawara, Katsunori, Shiiba, Masashi, Tanzawa, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069674/
https://www.ncbi.nlm.nih.gov/pubmed/24961284
http://dx.doi.org/10.1038/srep05433