Preparation and characterization of celecoxib solid dispersions; comparison of poloxamer-188 and PVP-K30 as carriers

OBJECTIVE(S): Solid dispersion formulation is the most promising strategy to improve oral bioavailability of poorly water soluble drugs. The aim of this study was to compare the effect of polyvinylpyrrolidone K30 (PVP) and poloxamer-188 (PLX) as carrier in solid dispersion formulations of celecoxib...

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Detalles Bibliográficos
Autores principales: Homayouni, Alireza, Sadeghi, Fatemeh, Nokhodchi, Ali, Varshosaz, Jaleh, Garekani, Hadi Afrasiabi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069839/
https://www.ncbi.nlm.nih.gov/pubmed/24967060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069839/
https://www.ncbi.nlm.nih.gov/pubmed/24967060

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