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Allopregnanolone suppresses diabetes-induced neuropathic pain and motor deficit through inhibition of GABA(A) receptor down-regulation in the spinal cord of diabetic rats
OBJECTIVE(S): Painful diabetic neuropathy is associated with hyperexcitability and hyperactivity of spinal cord neurons. However, its underlying pathophysiological mechanisms have not been fully clarified. Induction of excitatory/inhibitory neurotransmission imbalance at the spinal cord seems to acc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Mashhad University of Medical Sciences
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069843/ https://www.ncbi.nlm.nih.gov/pubmed/24967058 |