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In-silico screening and in-vitro validation of Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) inhibitors

VEGFR-2 tyrosine kinase receptor draws attention of the scientific fraternity in drug discovery for its important role in cancer, cardiopulmonary, cardiovascular diseases etc. Hence there is a need for novel VEGFR-2 inhibitors screening and testing for their biological activities. The 3D-structure w...

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Detalles Bibliográficos
Autores principales: Saraswat, Deepika, Nehra, Sarita, Chaudhary, Kamal Kumar, Prasad, C.V.S. Siva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070036/
https://www.ncbi.nlm.nih.gov/pubmed/24966534
http://dx.doi.org/10.6026/97320630010273