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Molecular docking studies of benzimidazopyrimidine and coumarin substituted benzimidazopyrimidine derivatives: As potential human Aurora A kinase inhibitors

Protein kinases are important drug targets in human cancers, inflammation and metabolic diseases. Docking studies was performed for all the benzimidazopyrimidine and coumarin substituted benzimidazopyridimine derivatives with human Aurora A kinase target (3FDN) employing flexible ligand docking appr...

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Detalles Bibliográficos
Autores principales: Chandra, Puttaraju, Kallimeledoddi B, Mahesh, Sankanahally Srinivasshetty, Shivashankar, Kalegowda, Lokanath, Neratur Krishnappagowda, Madegowda, Mahendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070038/
https://www.ncbi.nlm.nih.gov/pubmed/24966536
http://dx.doi.org/10.6026/97320630010288