Evaluation of novel Saquinavir analogs for resistance mutation compatibility and potential as an HIV-Protease inhibitor drug

A fundamental issue related to therapy of HIV-1 infection is the emergence of viral mutations which severely limits the long term efficiency of the HIV-protease (HIV-PR) inhibitors. Development of new drugs is therefore continuously needed. Chemoinformatics enables to design and discover novel molec...

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Detalles Bibliográficos
Autores principales: Jayaswal, Amit, Mishra, Ankita, Mishra, Hirdyesh, Shah, Kavita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2014
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070054/
https://www.ncbi.nlm.nih.gov/pubmed/24966525
http://dx.doi.org/10.6026/97320630010227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070054/
https://www.ncbi.nlm.nih.gov/pubmed/24966525
http://dx.doi.org/10.6026/97320630010227

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