An adaptive permutation approach for genome-wide association study: evaluation and recommendations for use

BACKGROUND: Permutation testing is a robust and popular approach for significance testing in genomic research, which has the broad advantage of estimating significance non-parametrically, thereby safe guarding against inflated type I error rates. However, the computational efficiency remains a chall...

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Detalles Bibliográficos
Autores principales: Che, Ronglin, Jack, John R, Motsinger-Reif, Alison A, Brown, Chad C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070098/
https://www.ncbi.nlm.nih.gov/pubmed/24976866
http://dx.doi.org/10.1186/1756-0381-7-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070098/
https://www.ncbi.nlm.nih.gov/pubmed/24976866
http://dx.doi.org/10.1186/1756-0381-7-9

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