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A broad survey reveals substitution tolerance of residues ligating FeS clusters in [NiFe] hydrogenase
BACKGROUND: In order to understand the effects of FeS cluster attachment in [NiFe] hydrogenase, we undertook a study to substitute all 12 amino acid positions normally ligating the three FeS clusters in the hydrogenase small subunit. Using the hydrogenase from Alteromonas macleodii “deep ecotype” as...
Autores principales: | Yonemoto, Isaac T, Clarkson, Benjamin R, Smith, Hamilton O, Weyman, Philip D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070099/ https://www.ncbi.nlm.nih.gov/pubmed/24934472 http://dx.doi.org/10.1186/1471-2091-15-10 |
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