Pentoxifylline decreases glycemia levels and TNF-alpha, iNOS and COX-2 expressions in diabetic rat pancreas

Pentoxifylline (PTX), a methyl xanthine derivative, is a phosphodiesterase inhibitor with anti-inflammatory and renoprotective effects in diabetic patients, among other properties. We studied PTX actions and mechanisms in reducing blood biochemical parameters, in diabetic rats. For diabetes inductio...

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Detalles Bibliográficos
Autores principales: Garcia, Francisca Adilfa O, Pinto, Sofia F, Cavalcante, Andrezza F, Lucetti, Lívia T, Menezes, Silvana MS, Felipe, Cícero Francisco B, Alves, Ana Paula NN, Brito, Gerly Anne C, Cerqueira, Gilberto S, Viana, Glauce SB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070224/
https://www.ncbi.nlm.nih.gov/pubmed/24991532
http://dx.doi.org/10.1186/2193-1801-3-283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070224/
https://www.ncbi.nlm.nih.gov/pubmed/24991532
http://dx.doi.org/10.1186/2193-1801-3-283

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