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Pentoxifylline decreases glycemia levels and TNF-alpha, iNOS and COX-2 expressions in diabetic rat pancreas
Pentoxifylline (PTX), a methyl xanthine derivative, is a phosphodiesterase inhibitor with anti-inflammatory and renoprotective effects in diabetic patients, among other properties. We studied PTX actions and mechanisms in reducing blood biochemical parameters, in diabetic rats. For diabetes inductio...
Autores principales: | Garcia, Francisca Adilfa O, Pinto, Sofia F, Cavalcante, Andrezza F, Lucetti, Lívia T, Menezes, Silvana MS, Felipe, Cícero Francisco B, Alves, Ana Paula NN, Brito, Gerly Anne C, Cerqueira, Gilberto S, Viana, Glauce SB |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070224/ https://www.ncbi.nlm.nih.gov/pubmed/24991532 http://dx.doi.org/10.1186/2193-1801-3-283 |
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