Astragalus membranaceus up-regulate Cosmc expression and reverse IgA dys-glycosylation in IgA nephropathy

BACKGROUND: Decreased Core I β3-Gal-T-specific molecular chaperone (Cosmc) expression induced IgA1 aberrant glycosylation is the main characteristic of IgA nephropathy (IgAN). This study tried to elucidate the effect of Astragalus membranaceus on Cosmc expression and IgA O-glycosylation of periphera...

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Detalles Bibliográficos
Autores principales: Ji, Ling, Chen, XiaoLei, Zhong, Xiang, Li, Zi, Yang, Lichuan, Fan, Junming, Tang, Wanxing, Qin, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070356/
https://www.ncbi.nlm.nih.gov/pubmed/24942185
http://dx.doi.org/10.1186/1472-6882-14-195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070356/
https://www.ncbi.nlm.nih.gov/pubmed/24942185
http://dx.doi.org/10.1186/1472-6882-14-195

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