RCAN1 Regulates Mitochondrial Function and Increases Susceptibility to Oxidative Stress in Mammalian Cells

Mitochondria are the primary site of cellular energy generation and reactive oxygen species (ROS) accumulation. Elevated ROS levels are detrimental to normal cell function and have been linked to the pathogenesis of neurodegenerative disorders such as Down's syndrome (DS) and Alzheimer's d...

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Detalles Bibliográficos
Autores principales: Peiris, Heshan, Dubach, Daphne, Jessup, Claire F., Unterweger, Petra, Raghupathi, Ravinarayan, Muyderman, Hakan, Zanin, Mark P., Mackenzie, Kimberly, Pritchard, Melanie A., Keating, Damien J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070399/
https://www.ncbi.nlm.nih.gov/pubmed/25009690
http://dx.doi.org/10.1155/2014/520316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070399/
https://www.ncbi.nlm.nih.gov/pubmed/25009690
http://dx.doi.org/10.1155/2014/520316

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