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RCAN1 Regulates Mitochondrial Function and Increases Susceptibility to Oxidative Stress in Mammalian Cells
Mitochondria are the primary site of cellular energy generation and reactive oxygen species (ROS) accumulation. Elevated ROS levels are detrimental to normal cell function and have been linked to the pathogenesis of neurodegenerative disorders such as Down's syndrome (DS) and Alzheimer's d...
Autores principales: | Peiris, Heshan, Dubach, Daphne, Jessup, Claire F., Unterweger, Petra, Raghupathi, Ravinarayan, Muyderman, Hakan, Zanin, Mark P., Mackenzie, Kimberly, Pritchard, Melanie A., Keating, Damien J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070399/ https://www.ncbi.nlm.nih.gov/pubmed/25009690 http://dx.doi.org/10.1155/2014/520316 |
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