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Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from mitochondria to the ER in cancer cells

BACKGROUND: Resistance to cell death in the presence of stressful stimuli is one of the hallmarks of cancer cells acquired during multistep tumorigenesis, and knowledge of the molecular mechanism of stress adaptation can be exploited to develop cancer-selective therapeutics. Mitochondria and the end...

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Detalles Bibliográficos
Autores principales: Park, Hye-Kyung, Lee, Ji-Eun, Lim, Jaehwa, Kang, Byoung Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070406/
https://www.ncbi.nlm.nih.gov/pubmed/24924916
http://dx.doi.org/10.1186/1476-4598-13-148