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Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from mitochondria to the ER in cancer cells
BACKGROUND: Resistance to cell death in the presence of stressful stimuli is one of the hallmarks of cancer cells acquired during multistep tumorigenesis, and knowledge of the molecular mechanism of stress adaptation can be exploited to develop cancer-selective therapeutics. Mitochondria and the end...
Autores principales: | Park, Hye-Kyung, Lee, Ji-Eun, Lim, Jaehwa, Kang, Byoung Heon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070406/ https://www.ncbi.nlm.nih.gov/pubmed/24924916 http://dx.doi.org/10.1186/1476-4598-13-148 |
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