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Lithium Chloride Suppresses Colorectal Cancer Cell Survival and Proliferation through ROS/GSK-3β/NF-κB Signaling Pathway

Glycogen synthase kinase-3β (GSK-3β), a serine/threonine protein kinase, has been regarded as a potential therapeutic target for multiple human cancers. In addition, oxidative stress is closely related to all aspects of cancer. We sought to determine the biological function of lithium, one kind of G...

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Detalles Bibliográficos
Autores principales: Li, Huili, Huang, Kun, Liu, Xinghua, Liu, Jinlin, Lu, Xiaoming, Tao, Kaixiong, Wang, Guobin, Wang, Jiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070474/
https://www.ncbi.nlm.nih.gov/pubmed/25002914
http://dx.doi.org/10.1155/2014/241864