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Reprogramming of Mice Primary Hepatocytes into Insulin-Producing Cells by Transfection with Multicistronic Vectors

The neogenesis of insulin-producing cells (IPCs) from non-beta-cells has emerged as a potential method for treating diabetes mellitus (DM). Many groups have documented that activation of pancreatic transcription factor(s) in hepatocytes can improve the hyperglycemia in diabetic mice. In the present...

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Detalles Bibliográficos
Autores principales: Luo, Haizhao, Chen, Rongping, Yang, Rui, Liu, Yan, Chen, Youping, Shu, Yi, Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070478/
https://www.ncbi.nlm.nih.gov/pubmed/25006589
http://dx.doi.org/10.1155/2014/716163