The Proteasome Inhibitor, MG132, Attenuates Diabetic Nephropathy by Inhibiting SnoN Degradation In Vivo and In Vitro

Transforming growth factor-β (TGF-β) has been shown to be involved in diabetic nephropathy (DN). The SnoN protein can regulate TGF-β signaling through interaction with Smad proteins. Recent studies have shown that SnoN is mainly degraded by the ubiquitin-proteasome pathway. However, the role of SnoN...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Yang, Chen, Nan, Qinling, Gao, Chenlin, Feng, Hong, Gou, Fang, Chen, Guo, Zhang, Zhihong, Yan, Pijun, Peng, Juan, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070544/
https://www.ncbi.nlm.nih.gov/pubmed/25003128
http://dx.doi.org/10.1155/2014/684765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070544/
https://www.ncbi.nlm.nih.gov/pubmed/25003128
http://dx.doi.org/10.1155/2014/684765

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