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Fast multiclonal clusterization of V(D)J recombinations from high-throughput sequencing

BACKGROUND: V(D)J recombinations in lymphocytes are essential for immunological diversity. They are also useful markers of pathologies. In leukemia, they are used to quantify the minimal residual disease during patient follow-up. However, the full breadth of lymphocyte diversity is not fully underst...

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Detalles Bibliográficos
Autores principales: Giraud, Mathieu, Salson, Mikaël, Duez, Marc, Villenet, Céline, Quief, Sabine, Caillault, Aurélie, Grardel, Nathalie, Roumier, Christophe, Preudhomme, Claude, Figeac, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070559/
https://www.ncbi.nlm.nih.gov/pubmed/24885090
http://dx.doi.org/10.1186/1471-2164-15-409