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Fast multiclonal clusterization of V(D)J recombinations from high-throughput sequencing
BACKGROUND: V(D)J recombinations in lymphocytes are essential for immunological diversity. They are also useful markers of pathologies. In leukemia, they are used to quantify the minimal residual disease during patient follow-up. However, the full breadth of lymphocyte diversity is not fully underst...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070559/ https://www.ncbi.nlm.nih.gov/pubmed/24885090 http://dx.doi.org/10.1186/1471-2164-15-409 |