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Efficient de novo assembly of large and complex genomes by massively parallel sequencing of Fosmid pools
BACKGROUND: Sampling genomes with Fosmid vectors and sequencing of pooled Fosmid libraries on the Illumina platform for massive parallel sequencing is a novel and promising approach to optimizing the trade-off between sequencing costs and assembly quality. RESULTS: In order to sequence the genome of...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070561/ https://www.ncbi.nlm.nih.gov/pubmed/24906298 http://dx.doi.org/10.1186/1471-2164-15-439 |