Autologous transplantation of GDNF-expressing mesenchymal stem cells protects against MPTP-induced damage in cynomolgus monkeys

Glial cell-derived neurotrophic factor (GDNF) has shown beneficial effects in models of Parkinson's disease. The mild results observed in the double-blind clinical trial by intraputamenal infusion of recombinant GDNF proteins warrant a search for alternative delivery methods. In this study, we...

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Detalles Bibliográficos
Autores principales: Ren, Zhenhua, Wang, Jiayin, Wang, Shuyan, Zou, Chunlin, Li, Xiaobo, Guan, Yunqian, Chen, Zhiguo, Zhang, Y. Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070584/
https://www.ncbi.nlm.nih.gov/pubmed/24071770
http://dx.doi.org/10.1038/srep02786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070584/
https://www.ncbi.nlm.nih.gov/pubmed/24071770
http://dx.doi.org/10.1038/srep02786

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