Using infective mosquitoes to challenge monkeys with Plasmodium knowlesi in malaria vaccine studies

BACKGROUND: When rhesus monkeys (Macaca mulatta) are used to test malaria vaccines, animals are often challenged by the intravenous injection of sporozoites. However, natural exposure to malaria comes via mosquito bite, and antibodies can neutralize sporozoites as they traverse the skin. Thus, intra...

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Detalles Bibliográficos
Autores principales: Murphy, Jittawadee R, Weiss, Walter R, Fryauff, David, Dowler, Megan, Savransky, Tatyana, Stoyanov, Cristina, Muratova, Olga, Lambert, Lynn, Orr-Gonzalez, Sachy, Zeleski, Katie Lynn, Hinderer, Jessica, Fay, Michael P, Joshi, Gyan, Gwadz, Robert W, Richie, Thomas L, Villasante, Eileen Franke, Richardson, Jason H, Duffy, Patrick E, Chen, Jingyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070636/
https://www.ncbi.nlm.nih.gov/pubmed/24893777
http://dx.doi.org/10.1186/1475-2875-13-215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070636/
https://www.ncbi.nlm.nih.gov/pubmed/24893777
http://dx.doi.org/10.1186/1475-2875-13-215

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