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RPN2-mediated glycosylation of tetraspanin CD63 regulates breast cancer cell malignancy

BACKGROUND: The tetraspanin CD63 is a highly N-glycosylated protein that is known to regulate cancer malignancy. However, the contribution of glycosylation of CD63 to cancer malignancy remains unclear. Previously, we reported that ribophorin II (RPN2), which is part of an N-oligosaccharyle transfera...

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Detalles Bibliográficos
Autores principales: Tominaga, Naoomi, Hagiwara, Keitaro, Kosaka, Nobuyoshi, Honma, Kimi, Nakagama, Hitoshi, Ochiya, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070641/
https://www.ncbi.nlm.nih.gov/pubmed/24884960
http://dx.doi.org/10.1186/1476-4598-13-134