Effect of the 3- and 4-Methyl Groups on the Opioid Receptor Properties of N-Substituted trans-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines

[Image: see text] N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines (2a,b) are opioid receptor antagonists where the antagonist properties are not due to the type of N-substituent. In order to gain a better understanding of the contribution that the 3- and 4-methyl groups make to the p...

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Detalles Bibliográficos
Autores principales: Kormos, Chad M., Cueva, Juan Pablo, Gichinga, Moses G., Runyon, Scott P., Thomas, James B., Brieaddy, Lawrence E., Mascarella, S. Wayne, Gilmour, Brian P., Navarro, Hernán A., Carroll, F. Ivy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070716/
https://www.ncbi.nlm.nih.gov/pubmed/24635568
http://dx.doi.org/10.1021/jm500184j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070716/
https://www.ncbi.nlm.nih.gov/pubmed/24635568
http://dx.doi.org/10.1021/jm500184j

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