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The interactomes of POU5F1 and SOX2 enhancers in human embryonic stem cells

The genes POU5F1 and SOX2 are critical for pluripotency and reprogramming, yet the chromosomal organization around these genes remains poorly understood. We assayed long-range chromosomal interactions on putative enhancers of POU5F1 and SOX2 genes in human embryonic stem cells (hESCs) using 4C-Seq t...

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Detalles Bibliográficos
Autores principales: Gao, Fan, Wei, Zong, An, Woojin, Wang, Kai, Lu, Wange
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070749/
https://www.ncbi.nlm.nih.gov/pubmed/23549118
http://dx.doi.org/10.1038/srep01588