Prostacyclin mediates endothelial COX-2-dependent neuroprotective effects during excitotoxic brain injury

In a previous study, we found that intracerebral administration of excitotoxin (RS)-(tetrazole-5yl) glycine caused increased neural damage in the brain in an endothelial COX-2 deleted mouse line (Tie2Cre COX-2(flox/flox)). In this study, we investigated whether prostacyclin might mediate this endoth...

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Detalles Bibliográficos
Autores principales: An, Ying, Belevych, Natalya, Wang, Yufen, Zhang, Hao, Nasse, Jason S, Herschman, Harvey, Chen, Qun, Tarr, Andrew, Liu, Xiaoyu, Quan, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Original Research 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070856/
https://www.ncbi.nlm.nih.gov/pubmed/24971026
http://dx.doi.org/10.2147/JIR.S63205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070856/
https://www.ncbi.nlm.nih.gov/pubmed/24971026
http://dx.doi.org/10.2147/JIR.S63205

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