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The genetic basis of ankylosing spondylitis: new insights into disease pathogenesis

Ankylosing spondylitis (AS) is a complex disease involving multiple risk factors, both genetic and environmental. AS patients are predominantly young men, and the disease is characterized by inflammation and ankylosis, mainly at the cartilage–bone interface and enthesis. HLA-B27 has been known to be...

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Detalles Bibliográficos
Autores principales: Tsui, Florence WL, Tsui, Hing Wo, Akram, Ali, Haroon, Nigil, Inman, Robert D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070859/
https://www.ncbi.nlm.nih.gov/pubmed/24971029
http://dx.doi.org/10.2147/TACG.S37325