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Dynamic imbalance between cancer cell subpopulations induced by Transforming Growth Factor Beta (TGF-β) is associated with a DNA methylome switch
BACKGROUND: Distinct subpopulations of neoplastic cells within tumors, including hepatocellular carcinoma (HCC), display pronounced ability to initiate new tumors and induce metastasis. Recent evidence suggests that signals from transforming growth factor beta (TGF-β) may increase the survival of th...
Autores principales: | Martin, Marion, Ancey, Pierre-Benoit, Cros, Marie-Pierre, Durand, Geoffroy, Le Calvez-Kelm, Florence, Hernandez-Vargas, Hector, Herceg, Zdenko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070873/ https://www.ncbi.nlm.nih.gov/pubmed/24898317 http://dx.doi.org/10.1186/1471-2164-15-435 |
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