P38 MAPK signaling underlies a cell autonomous loss of stem cell self-renewal in aged skeletal muscle

Skeletal muscle aging results in a gradual loss of skeletal muscle mass, skeletal muscle function and decreased regenerative capacity, which can lead to sarcopenia and increased mortality. While the mechanisms underlying sarcopenia remain unclear, the skeletal muscle stem cell, or satellite cell, is...

Descripción completa

Detalles Bibliográficos
Autores principales: Bernet, Jennifer D., Doles, Jason D., Hall, John K., Kelly-Tanaka, Kathleen, Carter, Thomas A., Olwin, Bradley B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070883/
https://www.ncbi.nlm.nih.gov/pubmed/24531379
http://dx.doi.org/10.1038/nm.3465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070883/
https://www.ncbi.nlm.nih.gov/pubmed/24531379
http://dx.doi.org/10.1038/nm.3465

Ejemplares similares