Cell Stress Induces Upregulation of Osteopontin via the ERK Pathway in Type II Alveolar Epithelial Cells

Osteopontin (OPN) is a multifunctional protein that plays important roles in cell growth, differentiation, migration and tissue fibrosis. In human idiopathic pulmonary fibrosis and murine bleomycin-induced lung fibrosis, OPN is upregulated in type II alveolar epithelial cells (AEC II). However, the...

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Detalles Bibliográficos
Autores principales: Kato, Aki, Okura, Takafumi, Hamada, Chizuru, Miyoshi, Seigo, Katayama, Hitoshi, Higaki, Jitsuo, Ito, Ryoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070890/
https://www.ncbi.nlm.nih.gov/pubmed/24963635
http://dx.doi.org/10.1371/journal.pone.0100106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070890/
https://www.ncbi.nlm.nih.gov/pubmed/24963635
http://dx.doi.org/10.1371/journal.pone.0100106

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