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Maternal Pravastatin Prevents Altered Fetal Brain Development in a Preeclamptic CD-1 Mouse Model

OBJECTIVE: Using an animal model, we have previously shown that preeclampsia results in long-term adverse neuromotor outcomes in the offspring, and this phenotype was prevented by antenatal treatment with pravastatin. This study aims to localize the altered neuromotor programming in this animal mode...

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Detalles Bibliográficos
Autores principales: Carver, Alissa R., Andrikopoulou, Maria, Lei, Jun, Tamayo, Esther, Gamble, Phyllis, Hou, Zhipeng, Zhang, Jiangyang, Mori, Susumu, Saade, George R., Costantine, Maged M., Burd, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071009/
https://www.ncbi.nlm.nih.gov/pubmed/24963809
http://dx.doi.org/10.1371/journal.pone.0100873