Influence of Domain Stability on the Properties of Human Apolipoprotein E3 and E4 and Mouse Apolipoprotein E

[Image: see text] The human apolipoprotein (apo) E4 isoform, which differs from wild-type apoE3 by the single amino acid substitution C112R, is associated with elevated risk of cardiovascular and Alzheimer’s diseases, but the molecular basis for this variation between isoforms is not understood. Hum...

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Detalles Bibliográficos
Autores principales: Nguyen, David, Dhanasekaran, Padmaja, Nickel, Margaret, Mizuguchi, Chiharu, Watanabe, Mayu, Saito, Hiroyuki, Phillips, Michael C., Lund-Katz, Sissel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071092/
https://www.ncbi.nlm.nih.gov/pubmed/24871385
http://dx.doi.org/10.1021/bi500340z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071092/
https://www.ncbi.nlm.nih.gov/pubmed/24871385
http://dx.doi.org/10.1021/bi500340z

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