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Lamotrigine Decreased Hippocampal Damage and Improved Vascular Risk Markers in a Rat Model of Pentylenetetrazole Induced Kindling Seizure

Various antiepileptic drugs (AEDs) especially enzyme-inducing AEDs might be associated with increased vascular risk, through impairment of the endogenous antioxidative ability which may trigger oxygen-dependent tissue injury. Lamotrigine (LTG) a non-enzyme-inducing AED has scarce information regardi...

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Detalles Bibliográficos
Autores principales: Haggag, Basma S, Hasanin, Amany H, Raafat, Mona H, Abdel Kawy, Hala S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071181/
https://www.ncbi.nlm.nih.gov/pubmed/24976768
http://dx.doi.org/10.4196/kjpp.2014.18.3.269