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Hes-1 SUMOylation by protein inhibitor of activated STAT1 enhances the suppressing effect of Hes-1 on GADD45α expression to increase cell survival

BACKGROUND: Hairy and Enhancer of split 1 (Hes-1) is a transcriptional repressor that plays an important role in neuronal differentiation and development, but post-translational modifications of Hes-1 are much less known. In the present study, we aimed to investigate whether Hes-1 could be SUMO-modi...

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Detalles Bibliográficos
Autores principales: Chiou, Hsin-Ying Clair, Liu, Shau-Yu, Lin, Cheng-Hsiung, Lee, Eminy HY
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071220/
https://www.ncbi.nlm.nih.gov/pubmed/24894488
http://dx.doi.org/10.1186/1423-0127-21-53