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Organizer-derived Bmp2 is required for the formation of a correct Bmp activity gradient during embryonic development

Bone morphogenetic proteins (Bmps) control dorsoventral patterning of vertebrate embryos through the establishment of a ventrodorsal gradient of the activated downstream cytoplasmic effectors Smad1/5/8. Some Bmp ligands are expressed in the ventral and lateral regions and in the organizer during gas...

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Detalles Bibliográficos
Autores principales: Xue, Yu, Zheng, Xiudeng, Huang, Lei, Xu, Pengfei, Ma, Yuanqing, Min, Zheying, Tao, Qinghua, Tao, Yi, Meng, Anming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071459/
https://www.ncbi.nlm.nih.gov/pubmed/24777107
http://dx.doi.org/10.1038/ncomms4766