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Investigation of Indolglyoxamide and Indolacetamide Analogues of Polyamines as Antimalarial and Antitrypanosomal Agents
Pure compound screening has previously identified the indolglyoxylamidospermidine ascidian metabolites didemnidine A and B (2 and 3) to be weak growth inhibitors of Trypanosoma brucei rhodesiense (IC(50) 59 and 44 μM, respectively) and Plasmodium falciparum (K1 dual drug resistant strain) (IC(50) 41...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071569/ https://www.ncbi.nlm.nih.gov/pubmed/24879541 http://dx.doi.org/10.3390/md12063138 |