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Gamma-secretase subunits associate in intracellular membrane compartments in Arabidopsis thaliana

Gamma-secretase is a multisubunit complex with intramembrane proteolytic activity. In humans it was identified in genetic screens of patients suffering from familial forms of Alzheimer’s disease, and since then it was shown to mediate cleavage of more than 80 substrates, including amyloid precursor...

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Detalles Bibliográficos
Autores principales: Smolarkiewicz, Michalina, Skrzypczak, Tomasz, Michalak, Michał, Leśniewicz, Krzysztof, Walker, J. Ross, Ingram, Gwyneth, Wojtaszek, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071823/
https://www.ncbi.nlm.nih.gov/pubmed/24723404
http://dx.doi.org/10.1093/jxb/eru147