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Gamma-secretase subunits associate in intracellular membrane compartments in Arabidopsis thaliana
Gamma-secretase is a multisubunit complex with intramembrane proteolytic activity. In humans it was identified in genetic screens of patients suffering from familial forms of Alzheimer’s disease, and since then it was shown to mediate cleavage of more than 80 substrates, including amyloid precursor...
Autores principales: | Smolarkiewicz, Michalina, Skrzypczak, Tomasz, Michalak, Michał, Leśniewicz, Krzysztof, Walker, J. Ross, Ingram, Gwyneth, Wojtaszek, Przemysław |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071823/ https://www.ncbi.nlm.nih.gov/pubmed/24723404 http://dx.doi.org/10.1093/jxb/eru147 |
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