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Identification of “safe harbor” loci in indica rice genome by harnessing the property of zinc-finger nucleases to induce DNA damage and repair

Zinc-finger nucleases (ZFNs) have proved to be successful tools for targeted genome manipulation in several organisms. Their main property is the induction of double-strand breaks (DSBs) at specific sites, which are further repaired through homologous recombination (HR) or non-homologous end joining...

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Detalles Bibliográficos
Autores principales: Cantos, Christian, Francisco, Perigio, Trijatmiko, Kurniawan R., Slamet-Loedin, Inez, Chadha-Mohanty, Prabhjit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071976/
https://www.ncbi.nlm.nih.gov/pubmed/25018764
http://dx.doi.org/10.3389/fpls.2014.00302