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Solution Structure and Molecular Determinants of Hemoglobin Binding of the First NEAT Domain of IsdB in Staphylococcus aureus

[Image: see text] The human pathogen Staphylococcus aureus acquires heme iron from hemoglobin (Hb) via the action of a series of iron-regulated surface determinant (Isd) proteins. The cell wall anchored IsdB protein is recognized as the predominant Hb receptor, and is comprised of two NEAr transport...

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Detalles Bibliográficos
Autores principales: Fonner, Brittany A., Tripet, Brian P., Eilers, Brian J., Stanisich, Jessica, Sullivan-Springhetti, Rose K., Moore, Rebecca, Liu, Mengyao, Lei, Benfang, Copié, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072347/
https://www.ncbi.nlm.nih.gov/pubmed/24871270
http://dx.doi.org/10.1021/bi5005188