LGR5 is required for the maintenance of spheroid-derived colon cancer stem cells

Colon cancer stem cells (CCSCs) are involved in colon cancer and promote tumor progression and recurrence. LGR5, a marker for intestinal stem cells (ISCs), is also considered to serve as a marker for CCSCs. However, the precise function of LGR5 in CCSCs is unclear. In this study, we demonstrated tha...

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Detalles Bibliográficos
Autores principales: CHEN, XIANG, WEI, BO, HAN, XIAOYAN, ZHENG, ZONGHENG, HUANG, JIANGLONG, LIU, JIANPEI, HUANG, YONG, WEI, HONGBO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072401/
https://www.ncbi.nlm.nih.gov/pubmed/24789370
http://dx.doi.org/10.3892/ijmm.2014.1752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072401/
https://www.ncbi.nlm.nih.gov/pubmed/24789370
http://dx.doi.org/10.3892/ijmm.2014.1752

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